🤖 GLOBAL HEALTH OPTIMIZATION AGENT v3.0

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🧬 Genetic Analysis

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📊 Resource Allocation by Research Phase:

📚 Data Analysis

🧪 Experimental Design

🔬 Clinical Trials

💊 Treatment Development

Trial Search

Current Search Criteria:

Intervention: 800 mg Grazoprevir

Found 15 matching trials

Efficacy and Safety of Combination Grazoprevir (MK-5172) + Elbasvir (MK-8742) + Ribavirin (RBV) in Genotype 2 Hepatitis C Infection (MK-5172-047)

PHASE2

This is a multi-site, open-label trial evaluating the safety and efficacy o...

Status

Completed

Location

Multiple Locations

Start Date

2013-10-01

Trial ID

NCT01932762

Treatments Being Tested

Grazoprevir Elbasvir Ribavirin

Elbasvir/Grazoprevir (EBR/GZR) and Sofosbuvir (SOF) With and Without Ribavirin (RBV) in Cirrhotic Subjects With Chronic Hepatitis C Virus (HCV) Genotype 3 (GT3) Infection (MK-5172-083)

PHASE2

This is a randomized, multi-site, open-label trial of the co-administration...

Status

Completed

Location

Multiple Locations

Start Date

2016-01-05

Trial ID

NCT02601573

Treatments Being Tested

Grazoprevir Elbasvir Ribavirin Sofosbuvir

A Study of Different Durations of Treatment With Grazoprevir (MK-5172) in Combination With Ribavirin in Participants With Chronic Hepatitis C (MK-5172-039)

PHASE2

This study will compare two different durations of treatment with grazoprev...

Status

Completed

Location

Multiple Locations

Start Date

2013-01-18

Trial ID

NCT01716156

Treatments Being Tested

Grazoprevir Ribavirin

Evaluation of Hepatic Pharmacokinetics for Grazoprevir (MK-5172) in Participants With Chronic Hepatitis C (MK-5172-022)

PHASE1

This study is divided into 2 segments, and proposes to qualify fine needle ...

Status

Withdrawn

Location

Multiple Locations

Start Date

2012-05

Trial ID

NCT01547312

Treatments Being Tested

Peg-Interferon Liver Samples from FNA Liver Samples from CNB Blood Samples Ribavirin 800 mg Grazoprevir 100 mg Grazoprevir Liver samples from CNB and FNA

Grazoprevir (MK-5172)/Elbasvir (MK-8742) Versus Boceprevir/Pegylated Interferon/Ribavarin for Chronic Hepatitis C Infection (MK-5172-066)

PHASE3

This is a randomized, multi-site, open-label trial of a fixed-dose combinat...

Status

Withdrawn

Location

Multiple Locations

Start Date

2014-11

Trial ID

NCT02204475

Treatments Being Tested

Grazoprevir/Elbasvir Boceprevir PegIntron Ribavarin

Study of Grazoprevir (MK-5172) + Elbasvir (MK-8742) + Ribavirin in Participants With Chronic Hepatitis C Who Failed Prior Direct-Acting Antiviral Therapy (MK-5172-048)

PHASE2

In this study, participants with hepatitis C virus (HCV) genotype 1 (GT1) w...

Status

Completed

Location

Multiple Locations

Start Date

2014-05-23

Trial ID

NCT02105454

Treatments Being Tested

Grazoprevir (GZR)Elbasvir (EBR)Ribavirin (RBV)

Efficacy and Safety of Grazoprevir (+) Uprifosbuvir (+) Ruzasvir (MK-3682B) (MK-5172 + MK-3682 + MK-8408) Fixed Dose Combination in Chronic HCV Participants Failing Prior Antiviral Treatment (MK-3682-021)

PHASE2

This is a randomized, multicenter, 2-part, open-label trial of the combinat...

Status

Terminated

Location

Multiple Locations

Start Date

2015-12-10

Trial ID

NCT02613403

Treatments Being Tested

MK-3682B Ribavirin

Grazoprevir (MK-5172) With Peg-Interferon and Ribavirin in Participants With Chronic Genotype 2 or 3 Hepatitis C (MK-5172-012)

PHASE2

This study will evaluate the safety, tolerability, and antiviral activity o...

Status

Terminated

Location

Multiple Locations

Start Date

2011-11-28

Trial ID

NCT01440595

Treatments Being Tested

Grazoprevir Placebo to Grazoprevir Peginterferon alfa-2b (Peg-IFN)Ribavirin (RBV)

Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Virus (HCV) Genotype (GT) 3, GT4, GT5, and GT6 Infection (MK-3682-012)

PHASE2

This is a randomized, three-part, parallel-group, open-label trial of grazo...

Status

Completed

Location

Multiple Locations

Start Date

2015-01-28

Trial ID

NCT02332720

Treatments Being Tested

Grazoprevir Uprifosbuvir Elbasvir Ruzasvir MK-3682B Ribavirin (RBV)

Grazoprevir (MK-5172) Administered With Peginterferon and Ribavirin in Treatment-Naïve Participants With Chronic Hepatitis C (MK-5172-003)

PHASE2

This study will evaluate the safety, tolerability, and antiviral activity o...

Status

Completed

Location

Multiple Locations

Start Date

2011-06-27

Trial ID

NCT01353911

Treatments Being Tested

Grazoprevir Boceprevir Placebo for Grazoprevir Placebo for Boceprevir Peg-interferon alfa-2b Ribavirin

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